pain

(noun) a symptom of some physical hurt or disorder. Synonyms: hurting. Examples: "The patient developed severe pain and distension."

(noun) emotional distress; a fundamental feeling that people try to avoid. Synonyms: painfulness. Examples: "The pain of loneliness."

(noun) a somatic sensation of acute discomfort. Synonyms: pain sensation, painful sensation. Examples: "As the intensity increased the sensation changed from tickle to pain."

(noun) a bothersome annoying person. Synonyms: pain in the neck, nuisance. Examples: "That kid is a terrible pain."

(noun) something or someone that causes trouble; a source of unhappiness. Synonyms: annoyance, bother, botheration, infliction, pain in the neck, pain in the ass. Examples: "Washing dishes was a nuisance before we got a dish washer." "A bit of a bother." "He's not a friend, he's an infliction."

(verb) cause bodily suffering to and make sick or indisposed. Synonyms: trouble, ail.

(verb) cause emotional anguish or make miserable. Synonyms: anguish, hurt. Examples: "It pains me to see my children not being taught well in school."