deranged

(verb) derange mentally, throw out of mental balance; make insane. Synonyms: unbalance, derange. Example: "The death of his parents unbalanced him."

(verb) throw into great confusion or disorder. Synonyms: perturb, derange, throw out of kilter. Example: "Fundamental islamicists threaten to perturb the social order in algeria and egypt."

(adj) driven insane. Synonyms: crazed, half-crazed.