unbalance

(noun) a lack of balance or state of disequilibrium. Synonyms: imbalance, instability. Example: "A hormonal imbalance."

(noun) a state of mental disturbance and disorientation. Synonyms: derangement, mental unsoundness.

(verb) throw out of balance or equilibrium. Examples: "The tax relief unbalanced the budget." "The prima donna unbalances the smooth work in our department."

(verb) derange mentally, throw out of mental balance; make insane. Synonyms: derange. Example: "The death of his parents unbalanced him."