sore

(noun) an open skin infection.

(adj) hurting. Synonyms: sensitive, raw, tender. Example: "The tender spot on his jaw."

(adj) causing misery or pain or distress. Synonyms: afflictive, painful. Examples: "It was a sore trial to him." "The painful process of growing up."

(adj) roused to anger. Synonyms: huffy, mad. Examples: "Stayed huffy a good while"- mark twain." "She gets mad when you wake her up so early." "Mad at his friend." "Sore over a remark."