ruination

(noun) an irrecoverable state of devastation and destruction. Synonyms: ruin. Example: "You have brought ruin on this entire family."

(noun) an event that results in destruction. Synonyms: ruin.

(noun) failure that results in a loss of position or reputation. Synonyms: downfall, ruin.

(noun) destruction achieved by causing something to be wrecked or ruined. Synonyms: laying waste, ruin, ruining, wrecking.