mortify

(verb) practice self-denial of one's body and appetites.

(verb) hold within limits and control. Synonyms: subdue, crucify. Examples: "Subdue one's appetites." "Mortify the flesh."

(verb) cause to feel shame; hurt the pride of. Synonyms: humiliate, chagrin, humble, abase. Examples: "He humiliated his colleague by criticising him in front of the boss."

(verb) undergo necrosis. Synonyms: necrose, gangrene, sphacelate. Examples: "The tissue around the wound necrosed."