mortification
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Definitions
(noun) the localized death of living cells (as from infection or the interruption of blood supply). Synonyms: necrosis, gangrene, sphacelus.
Noun Definition 2
(noun) an instance in which you are caused to lose your prestige or self-respect. Synonyms: humiliation. Example: "He had to undergo one humiliation after another."
Noun Definition 3