handicap

(noun) the condition of being unable to perform as a consequence of physical or mental unfitness. Synonyms: disability, disablement, impairment. Examples: "Reading disability." "Hearing impairment."

(noun) advantage given to a competitor to equalize chances of winning.

(noun) something immaterial that interferes with or delays action or progress. Synonyms: hindrance, hinderance, deterrent, impediment, balk, baulk, check.

(verb) injure permanently. Synonyms: disable, invalid, incapacitate. Example: "He was disabled in a car accident."

(verb) attempt to forecast the winner (especially in a horse race) and assign odds for or against a contestant.

(verb) put at a disadvantage. Synonyms: hinder, hamper. Example: "The brace i have to wear is hindering my movements."