extremity

(noun) an external body part that projects from the body. Synonyms: appendage, member. Examples: "It is important to keep the extremities warm."

(noun) an extreme condition or state (especially of adversity or disease).

(noun) the greatest or utmost degree. Examples: "The extremity of despair."

(noun) the outermost or farthest region or point.

(noun) that part of a limb that is farthest from the torso.