extirpate

(verb) destroy completely, as if down to the roots. Synonyms: uproot, eradicate, root out, exterminate. Example: "The vestiges of political democracy were soon uprooted" "root out corruption."

(verb) pull up by or as if by the roots. Synonyms: uproot, deracinate, root out. Example: "Uproot the vine that has spread all over the garden."

(verb) surgically remove (an organ).