callous

(verb) make insensitive or callous; deaden feelings or morals. Synonyms: cauterize, cauterise.

(adj) emotionally hardened. Synonyms: indurate, pachydermatous. Examples: "A callous indifference to suffering." "Cold-blooded and indurate to public opinion."

(adj) having calluses; having skin made tough and thick through wear. Synonyms: calloused, thickened. Examples: "Calloused skin." "With a workman's callous hands."