alienate

(verb) arouse hostility or indifference in where there had formerly been love, affection, or friendliness. Synonyms: estrange, alien, disaffect. Example: "She alienated her friends when she became fanatically religious."

(verb) transfer property or ownership. Synonyms: alien. Example: "The will aliened the property to the heirs."

(verb) make withdrawn or isolated or emotionally dissociated. Example: "The boring work alienated his employees."