abnormality

(noun) an abnormal physical condition resulting from defective genes or developmental deficiencies. Synonyms: abnormalcy.

(noun) retardation sufficient to fall outside the normal range of intelligence. Synonyms: mental defectiveness.

(noun) marked strangeness as a consequence of being abnormal. Synonyms: freakishness.

(noun) behavior that breaches the rule or etiquette or custom or morality. Synonyms: irregularity.