incapacitating

(verb) make unable to perform a certain action. Synonyms: disable, disenable, incapacitate. Example: "Disable this command on your computer."

(verb) injure permanently. Synonyms: disable, invalid, incapacitate, handicap. Example: "He was disabled in a car accident."

(adj) that cripples or disables or incapacitates. Synonyms: crippling, disabling. Example: "A crippling injury."