estranged

(verb) remove from customary environment or associations. Synonyms: estrange. Example: "Years of boarding school estranged the child from her home."

(verb) arouse hostility or indifference in where there had formerly been love, affection, or friendliness. Synonyms: estrange, alienate, alien, disaffect. Example: "She alienated her friends when she became fanatically religious."

(adj) caused to be unloved. Synonyms: alienated.